Weight Loss Can Control Hypertension

Mar. 23 -- FRIDAY, Sept. 28 (HealthDay News) -- An Italian study has identified overweight as a direct cause of high blood pressure. And it also showed that up to half of overweight people can bring down blood pressure to healthy levels by weight reduction.

But the weight loss has to be achieved before the borderline to outright obesity is crossed, said Dr. Roberto Fogari, professor of medicine at the University of Pavia. He was to present the study findings Friday at the annual meeting of the American Heart Association's Council for High Blood Pressure Research, in Tucson, Ariz.

It's important that the study linked overweight to high blood pressure, which usually is described as "essential," a medical term meaning that the cause is unknown, Fogari said.

"The study suggests that, in many cases, hypertension [high blood pressure] is not essential," he said. "It is secondary to overweight. So, in the first stages of overweight, if we can induce people to reduce overweight, they can also avoid being treated for hypertension."

The study included 210 men and women whose body mass index [a ratio of weight to height] was between 25 and 29.9, indicating overweight but just short of the 30 mark of obesity. Their systolic blood pressure was between 140 and 159, and their diastolic pressure was between 90 and 99, indicating moderately high blood pressure.

An individualized low-calorie diet was designed for each study participant. Some also were prescribed orlistat, a drug that prevents fat from being metabolized.

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After six months, 53 percent of the men and 49 percent of the women in the study achieved normal body weight, and a 5 percent reduction in blood pressure.

"The other 50 percent of those in the study already had abnormal changes in the vascular tree [blood vessel system], so that hypertension was no longer reversible by losing weight," Fogari said.

The implication for practicing physicians who see moderately overweight people with high blood pressure is that their first goal should be weight reduction, he said.