Ohio has the nation's second-highest total of pediatric COVID-19 hospitalizations.
As of Wednesday morning, more than 210 children were hospitalized with COVID-19 in the state.
Children appear to be getting sicker than at previous points in the pandemic, according to front-line workers, particularly adolescents who have not been vaccinated.
Dayton Children's Hospital is among those impacted. Hospital officials say they've seen a record number of patients since the end of the summer.
"[It's] pretty hard to keep our heads above water, day in and day out," charge nurse Will Andres told ABC News.
Another concerning trend, doctors say, is the number of children who are forced to stay alone in the hospital because their parents are also battling COVID-19.
Michele Nadolsky, a clinical team leader in the emergency room, added, "One of our biggest concerns is what's going to happen in six months to a year from now, after [the] child has recovered from the acute illness of COVID-19, and what kind of symptoms or long-term effect is it going to have on them."
-ABC News' Arielle Mitropoulos