The U.S. said Iran launched ballistic missiles toward regional neighbors.
President Donald Trump announced "major combat operations" against Iran on Feb. 28, with massive joint U.S.-Israeli strikes targeting military, government and infrastructure sites.
Following the announcement of a two-week ceasefire, initial U.S.-Iran talks in Pakistan in April failed to reach a peace deal.
Trump later announced the open-ended extension of the ceasefire and the continuation of a U.S. blockade until negotiations are concluded "one way or the other."
An additional wave of Iranian drones "attempting to attack U.S. forces in Kuwait failed to impact intended targets" on Tuesday night, U.S. Central Command said in a social media statement.
"U.S. Central Command air defenses successfully downed multiple drones and ensured no American personnel or assets were harmed," the statement said.
U.S. forces helped intercept Iranian missiles and conducted "self-defense" strikes on Qeshm Island, following "attempted attacks" by Iran in the Middle East on Tuesday, U.S. Central Command said.
"Iran launched several ballistic missiles toward regional neighbors; however, all failed to hit their intended targets," CENTCOM said in a statement.
Two missiles launched at Kuwait were unsuccessful, while three fired at Bahrain were intercepted by U.S. and Bahrain air defense forces, CENTCOM said.
U.S. forces also shot down multiple attack drones launched by Iran "toward civilian mariners that were rightfully transiting regional waters," CENTCOM said.
The self-defense strikes on Qeshm Island targeted an Iranian military ground control station, according to CENTCOM.
No U.S. personnel were harmed in the attacks, CENTCOM said.
The Kuwait Army said its air defenses are "currently confronting hostile missile and drone attacks."
It did not say from where the attacks originated.
The army told residents to follow instructions from authorities and that they may hear explosions due to air defenses intercepting the attacks.
U.S. Central Command disabled an oil tanker that it said failed to comply with the U.S. naval blockade in the Arabian Gulf on Tuesday.
"A U.S. aircraft ultimately disabled the vessel by firing a Hellfire missile into the ship's engine room, preventing the tanker from reaching Iran," CENTCOM said in a social media post that included a video of the strike.
CENTCOM said the oil tanker was attempting to sail toward an Iranian port. It is the sixth commercial vessel disabled since the blockade took effect, the military said.
