Iran live updates: Trump says agreement with Iran could be signed as early as this weekend

For a second night in a row, the U.S. military is striking "multiple targets" in Iran on President Donald Trump's orders, according to a post by U.S. Central Command.

"U.S. Central Command forces began launching additional self-defense strikes today at 5:15 p.m. ET against multiple targets in Iran at the Commander in Chief's direction," CENTCOM said in a post. "The strikes are in response to Iran’s unwarranted and continued aggression."

Defense Secretary Pete Hegseth said the U.S. military "will be busy tonight" in Iran during remarks after visiting the U.S. Central Command headquarters in Tampa, Florida, on Wednesday.

"Central Command will be busy tonight because President Trump said we will be hitting Iran hard, and we will be. Because Iran has a chance to make a good deal, a great deal to codify what they said they've been willing to do, and they haven't been willing to do it," Hegseth told reporters.

"As President Trump said, they've been tap, tap, tapping. You can see when someone's trying to tap, tap, tap on a deal. Instead, they're going to have tap, tap, tap bombs dropping on key facilities in Iran from the United States of America," Hegseth continued. "And that's not because we want to restart anything we don't have to restart. It's because we are, the War Department is prepared to set the terms to ensure that we get the kind of deal President Trump expects."

Israel Defense Minister Israel Katz threatened force against Iran if it strikes Israel again, saying the war is "far from over."

"We must not think that the work is done, the campaign against Iran is far from over. If Iran attacks Israel, it will suffer a severe blow, as we did a few days ago. The IDF is prepared to attack Iran with great force," Katz said speaking in Jerusalem on Wednesday.

"We continue to attack Hezbollah terrorists everywhere for the sake of the security of the northern communities and the State of Israel, and we categorically reject Iran's threats and its attempt to link the arenas," he said.

Iranian President Masoud Pezeshkian says the country will "stand firm" amid threats from the U.S. of more attacks against the country, denouncing threats against Iranian infrastructure.

"Threats to target them – from transportation networks to the electricity and water industries – are not a show of strength but a sign of desperation in the face of a nation’s will,” he said.

Pezeshkian’s post comes after President Donald Trump said his administration would be “attacking [Iran] very hard."

Iran "will stand firm against any pressure or threat," Pezeshkian said.