As Iran retaliates, largest US military base in Middle East hit by ballistic missile, Qatar says

The Iranian Ministry of Interior condemned the joint attack by U.S. and Israel on Saturday, saying in a statement released through Iran’s state broadcaster IRIB: "We would like to inform the great people of Islamic Iran that the criminal enemy has once again violated all international laws and during negotiations, once again violated our beloved homeland."

Earlier, the Islamic Revolutionary Guard Corps issued a statement via Iranian state broadcaster IRIB saying an attack on Israel had begun.

"In response to the aggression of the hostile and criminal enemy against the Islamic Republic of Iran, the first wave of widespread missile and drone attacks by the Islamic Republic of Iran against the occupied territories has begun," the IRGC said.

The U.S. embassy in Qatar is warning Americans in the country of imminent missile strikes.

"Missile incoming. Imminent missile strikes. Duck and cover until further notice. Continue to shelter in place," the notice said.

The U.S. strikes involve a mix of U.S. aircraft and Tomahawk cruise missiles fired by U.S. Navy ships in the region according to a U.S. official.

-ABC News' Luis Martinez

In a post on social media, the Pentagon posted the name of the military operation: "Operation Epic Fury."