As Iran retaliates, largest US military base in Middle East hit by ballistic missile, Qatar says

Sen. Tim Kaine, D-Va., is calling on the Senate to return to Washington immediately to vote on a war powers resolution to check the president's authority to wage war with Iran, calling the military action "idiotic."

“Has President Trump learned nothing from decades of U.S. meddling in Iran and forever wars in the Middle East? Is he too mentally incapacitated to realize that we had a diplomatic agreement with Iran that was keeping its nuclear program in check, until he ripped it up during his first term?," Kaine said in a statement Saturday.

“For months, I have raised hell about the fact that the American people want lower prices, not more war—especially wars that aren’t authorized by Congress, as required by the Constitution, and don’t have a clear objective. These strikes are a colossal mistake, and I pray they do not cost our sons and daughters in uniform and at embassies throughout the region their lives," he added.

Iranian Foreign Minister Abbas Araghchi said the U.S.-Israel strikes were “wholly unprovoked, illegal, and illegitimate.”

"Trump has turned 'America First' into 'Israel First'—which always means 'America Last,’ Araghchi wrote in a post on X Saturday. "Our Powerful Armed Forces are prepared for this day and will teach the aggressors the lesson they deserve."

Araghchi shared a screenshot of an October 2012 social media post from President Donald Trump.

“Now that Obama’s poll numbers are in tailspin - watch for him to launch a strike in Libya or Iran. He is desperate," Trump wrote in the post on X.

-ABC News' Somayeh Malekian

The Omani Foreign Minister Badr Al Busaidi, who had been mediating U.S.-Iran talks and had traveled to Washington, D.C., on Friday, posted on X saying, "I am dismayed" and that "Active and serious negotiations have yet again been undermined."

"I urge the United States not to get sucked in further. This is not your war," he said.

-ABC News' Lama Hasan

Three sources briefed on the U.S.-Israeli attack told ABC News that Iran's Supreme Leader Ayatollah Ali Khamenei and President Masoud Pezeshkian were both targeted.