The Iranian response was sent via Pakistan on Sunday, state media said.
President Donald Trump announced "major combat operations" against Iran on Feb. 28, with massive joint U.S.-Israeli strikes targeting military, government and infrastructure sites.
Following the announcement of a two-week ceasefire, initial U.S.-Iran talks in Pakistan in April failed to reach a peace deal.
Trump later announced the open-ended extension of the ceasefire and the continuation of a U.S. blockade until negotiations are concluded "one way or the other."
The U.S. Central Command said it has redirected 57 commercial vessels and disabled 4 others to prevent the ships from entering or leaving Iranian ports.
-ABC News' Steven Beynon
Referring to negotiations with the U.S., Iranian Foreign Ministry spokesperson Esmaeil Baqaei said the country doesn't follow anyone's deadlines.
"The matter is still under discussion," Baqaei said. "We do our own job. We are not bound by their deadlines or timelines very much."
Secretary of State Marco Rubio told reporters the administration expected a response from the Iranian regime on Friday, but that "only stupid countries" wouldn’t respond to fire with fire when facing attacks like the U.S. did in the Strait of Hormuz.
"The red line is clear: They threaten Americans, they're gonna get blown up," Rubio told reporters Friday.
"If you fire at a U.S. Navy ship, what are we supposed to do?" Rubio said. "Of course we fired back on them. They were shooting at us. That's what I would expect to do. Only stupid countries don't shoot back when you're shot at," Rubio said. "And we're not a stupid country."
On talks with the regime, Rubio said “we should know something today” and “the hope is it's something that it can put us into a serious process of negotiation.”
“We're expecting a response from them today, at some point. We have not received that yet as—in the last in the last hour, but perhaps that will come. Their system is still highly fractured and a bit dysfunctional as well, so that may be serving as an impediment,” Rubio said. "I hope it's a serious offer. I really do."
-ABC News' Shannon K. Kingston
United Arab Emirates air defenses engaged two ballistic missiles and three drones launched by Iran on Friday, the UAE Ministry of Defense said in a post on X.
The attack resulted in three "moderate" injuries, the ministry said.
