State Department tells Americans worldwide to 'exercise increased caution'

President Donald Trump said the U.S. will "hit and obliterate" Iranian power plants if the Strait of Hormuz isn't opened within 48 hours

"If Iran doesn’t FULLY OPEN, WITHOUT THREAT, the Strait of Hormuz, within 48 HOURS from this exact point in time, the United States of America will hit and obliterate their various POWER PLANTS, STARTING WITH THE BIGGEST ONE FIRST!" Trump said in a post on his social media platform.

The largest power plant in Iran is thought to be the Damavand Combined Cycle Power Plant — which is located in the outskirts of the capital city Tehran.

Iran has effectively blocked the Strait of Hormuz -- a narrow waterway off Iran’s southern coast that normally handles about 20% of global oil consumption -- since the start of the war.

Trump's post came as he floated on Friday that he was considering "winding down" the U.S.'s military campaign, claiming the U.S. was "very close to meeting our objectives."

Trump also said Friday that the U.S. would "help" Gulf states secure and police the Strait of Hormuz "if asked."

Israel's MDA service said Saturday that 64 people were injured in an Iranian attack on the city of Arad in southern Israel.

Of those wounded, seven patients were in serious condition and 15 patients in moderate condition, according to MDA.

IDF Spokesperson Effie Defrin said the hits in Arad and earlier in Dimona on Saturday were direct missile strikes.

"The air defense systems were activated but did not intercept the missile. We will investigate the incident and learn from it," he said.

-ABC News' Dana Savir and Victoria Beaule

Israel Fire and Rescue said a building was hit during an Iranian missile attack in Dimona in southern Israel.

The Israel Defense Forces said attempts were made to intercept the missile and that the incident is being reviewed.

Israeli emergency services said they treated 47 people, including a 10-year-old boy in serious condition and a woman in moderate condition, both due to shrapnel wounds.

The Negev Nuclear Research Center, which officially carries out only general scientific nuclear research, lies just outside Dimona. The International Atomic Energy Agency said it was "aware of reports of an incident in the city of Dimona, Israel, involving a missile impact and has not received any indication of damage to the nuclear research center Negev."

-ABC News' Victoria Beaule

Iran is continuing to fire missiles and drones at countries in the region, including Kuwait and the United Arab Emirates.

Air defenses in Kuwait intercepted nine ballistic missiles and four drones that entered its airspace over the last 24 hours, the Kuwait Army General Staff Headquarters said in a post on X on Saturday.

The United Arab Emirates Ministry of Defense announced on Saturday air defense systems engaged three ballistic missile and eight drones launched from Iran.

-ABC News' Othon Leyva