US aircraft carrier strike group arrives in Middle East

The United Nations Office for the Coordination of Humanitarian Affairs published a new report Wednesday warning that food prices in some parts of Syria have increased by 900% amid the collapse of former President Bashar Assad's regime.

"Food shortages were reported in Deir el-Zour, Damascus and Hama; bread prices Idlib and Aleppo rose by 900% from Nov. 27 to Dec. 9," the UNOCHA wrote, referring to the period between the start of the surprise rebel offensive in the northwest and the fall of Damascus.

"Around 100,000 individuals have been displaced to northeast Syria," the report continued. "Hospitals are overwhelmed with trauma and injury cases and there is significant psychological distress, especially among children," it added.

The "fluid displacements" of large numbers of people are particularly concerning given the many areas of continued fighting and minefields across the country, the UNOCHA said. Those include 52 minefields identified in the past 10 days, it said.

-ABC News' Somayeh Malekian

Syrian rebel forces said late Tuesday they had taken control of the eastern city of Deir el-Zour on the banks of the Euphrates River and close to U.S. military positions in the region.

The city was occupied by Kurdish-led Syrian Democratic Forces on Dec. 6 as former president Bashar Assad's forces withdrew. The SDF subsequenty faced protests from residents and local officials.

The Hayat Tahrir al-Sham Military Operations Department said in a post to Telegram that the city and its military airport were "completely liberated" as of the early hours of Wednesday.

Geolocated videos showed rebel fighters in the city center, joined by residents waving the Syrian revolutionary flag.

Rebel forces continued to advance into the countryside to the west and east of the city, Lt. Col. Hassan Abdul Ghani said in a statement posted to Telegram.

Deir el-Zour is the largest city in eastern Syria and the closest to U.S. troop concentrations along the Euphrates River running to the Iraqi border.

-ABC News' Helena Skinner

Iranian Supreme Leader Ayatollah Ali Khamenei alleged on Wednesday that the U.S. and Israel orchestrated the rapid collapse of the Syrian government led by former President Bashar Assad.

Damascus' defeat, Khamenei wrote on X, "was planned in the U.S.-Israeli control room."

"We have evidence for this" which leaves "no room for doubt," Khamenei said.

Iran and Russia were the key backers of Assad's government through more than a decade of civil war.

Tehran's support for the regime in Damascus enabled Iran's Islamic Revolutionary Guard Corps to establish a major presence inside Syria alongside a range of Iran-backed militias, including Lebanese Hezbollah.

After dedicating his life to fighting the Assad regime, Mazen Al-Hamada did not live to see it fall.

A symbol of resilience and courage, the famous Syrian activist was found dead in the "slaughterhouse" prison of Saydnaya in Damascus, where he had been held since he returned to Syria in February 2020.

An unverified photo circulating online shows his disfigured face and suggests he was killed just before the rebels reached the prison, according to independent observers.

Al-Hamada was first arrested in 2011, when he protested against the regime, and remained in prison for two years. He left Syria in 2013 and was granted asylum in the Netherlands a year later.

That's when the world got to know the horrors he endured, which he bravely described as he spoke to huge crowds, policymakers and the press, voicing the struggle of thousands who like him were detained by Assad's regime -- at least 157,000 between 2011 and August 2024, according to a report by the Syrian Network for Human Rights.

“I will not rest until I take them to court and get justice,” Al-Hamada said in an interview for a 2017 documentary, ‘Syria's Disappeared,’ his sunken eyes in tears unable to hide the pain behind his words. “Justice for me and my friends who they killed. Even if it costs my life. Bring them to justice, no matter what."

-ABC News' Camilla Alcini