Highlights from Senate vote to confirm Ketanji Brown Jackson

Questioning over the next two days could prove critical to the White House goal of securing at least some Republican support for Judge Jackson's confirmation.

Three Republicans -- Sens. Susan Collins, Lisa Murkowski and Lindsey Graham -- voted in favor of Jackson's confirmation to the D.C. Circuit last June, but after private meetings with Biden's nominee this month, all three were noncommittal about supporting her again.

Jackson has been vetted twice previously by the Judiciary Committee and twice confirmed by the full Senate as a judge. She was also Senate confirmed in 2010 as vice-chair of the U.S. Sentencing Commission.

No Republican senator has publicly disputed Jackson's qualification to be a justice, though several have raised concerns about her rulings and presumed judicial philosophy, which she has insisted she does not have.

Even without bipartisan support, Democrats have the votes on their own for Jackson's confirmation, which party leaders have said they plan to complete before Easter.

-ABC News’ Devin Dwyer

Confirmation hearings for Judge Jackson -- the first Black woman to be considered for the U.S. Supreme Court -- continue on Tuesday at 9 a.m. when she'll face up to 19 hours of questions from Senate Judiciary Committee members over two days.

Jackson will lean on her three prior experiences being questioned by the Judiciary Committee -- more than any other nominee in 30 years -- as its 11 Republicans and 11 Democrats take turns probing her judicial philosophy, her record as a public defender and her legal opinions spanning nearly nine years on the bench.

Jackson has spent the past few weeks practicing for the spotlight during mock sessions conducted with White House staff, sources familiar with the preparations told ABC News. She also met individually with each of the committee's members and 23 other senators from both parties.

Each senator will get a 30-minute solo round of questioning on Tuesday, totaling more than 11 hours if each uses all of his or her allotted time, ahead of 20-minute rounds on Wednesday. The grilling is unlike any other for federal judges or political nominees in large part because of the lifetime tenure on the line.

-ABC News’ Devin Dwyer

On Tuesday, Jackson will lean on her three prior experiences being questioned by the Judiciary Committee -- more than any other nominee in 30 years -- as its 11 Republicans and 11 Democrats take turns probing her judicial philosophy, her record as a public defender and her legal opinions spanning nearly nine years on the bench.

Jackson has spent the past few weeks practicing for the spotlight during mock sessions conducted with White House staff, sources familiar with the preparations told ABC News.

Each senator will get a 30-minute solo round of questioning on Tuesday, totaling more than 11 hours if each uses all of his or her allotted time. The grilling is unlike any other for federal judges or political nominees in large part because of the lifetime tenure on the line.

-ABC News' Devin Dwyer

Senate Majority Leader Chuck Schumer said Monday he remains "confident" that the Senate is on track to confirm Jackson as 116th justice of the Supreme Court "by the end of this work period," which concludes April 8.

"Over the course of the week, I expect the American people will finally see for themselves why Judge Jackson is one of the most-qualified individuals ever to be nominated to the Supreme Court of the United States," Schumer said.

The Democrat continued, "I also trust that Americans will see right through the misleading and desperate broadsides that a few members of the other side have launched against the judge in recent weeks."

"We need not pretend that wild accusations from self-interested actors deserve to be taken seriously," he said. "So color me skeptical that the American people will give them much weight."

-ABC News' John Parkinson