Catherine Cortez Masto’s victory in Nevada clinched the chamber for Democrats.
The 2022 midterm elections shaped up to be some of the most consequential in the nation's recent history, with control of Congress at stake.
All 435 seats in the House and 35 of 100 seats in the Senate were on the ballot, as well as several influential gubernatorial elections in battleground states like Arizona, Georgia, Pennsylvania and Wisconsin.
Democrats were defending their narrow majorities in both chambers and retained control of the Senate, though control of the House isn't yet clear. But a Republican flip of the lower chamber would be enough to curtail most of President Joe Biden's legislative agenda and would likely result in investigations against his administration and even his family.
Asked Wednesday how he feels about the Republicans’ chances of taking back the Senate, Minority Leader Mitch McConnell replied, "I don’t deal in feelings.”
“They’ve got to count the votes and then we’ll figure out where we are,” he told reporters at the Capitol.
McConnell did not respond to ABC News’ questions if he's still supporting Georgia Republican Senatorial candidate Herschel Walker.
-ABC News’ Trish Turner
President Joe Biden will give remarks and hold a press conference at 4 p.m.
In a brief preview of his speech shared on Twitter, Biden thanked election officials for upholding democracy.
"Democracy doesn't happen by accident. We have to defend, strengthen and renew it," Biden tweeted.
"I'll have more to say this afternoon, but thanks to the poll workers and officials that worked into the night to safeguard our sacred right to vote. And the millions who made their voices heard," he continued.
Republican incumbent Ron Johnson is projected to win the Wisconsin Senate race over Democratic challenger Lt. Gov. Mandela Barnes.
With 94% of the vote reporting, Johnson has 51% of the vote and Barnes has 49%.
In a concession speech Wednesday, Barnes said, "It's time for us to double down. To show up like we've never shown up before. To make sure that Ron Johnson -- every political leader -- knows to answer to every person in Wisconsin, not just the people that voted for them."
Johnson was first elected in 2010 and is serving his second term in Congress, sitting on committees including the Senate Foreign Relations committee. He campaigned on being tough on crime and has faced backlash over comments about COVID-19 vaccines and the Jan. 6. insurrection. Johnson was the subject of part of the Jan. 6 committee's findings earlier this year which revealed, according to text messages from a senior Johnson aide, that he apparently wanted to deliver fake electoral votes for Donald Trump from Wisconsin and Michigan to Mike Pence on Jan. 6, 2021.
Barnes is the first Black lieutenant governor in Wisconsin and would have been the state's first Black senator had he won. He faced some opposition over his positions on crime and support from progressives.
Wisconsin went for Biden by a slim margin in 2020 after going for Trump in 2016.
-ABC News' Oren Oppenheim
Rep. Sean Patrick Maloney of New York on Wednesday called his Republican challenger Mike Lawler to concede. Political insiders say this was a big loss for Democrats.
Maloney is the chairman of the Democratic Congressional Campaign Committee, the fundraising arm for the House. He directed millions to save his own campaign and insisted he wasn’t in real trouble, potentially costing his colleagues votes.
-ABC News’ Rick Klein and Aaron Katersky
