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As more amendments are called for votes, Republicans continue to huddle behind the scenes to chart a path to ending the marathon vote-a-rama and passing President Donald Trump's megabill.

It appears increasingly clear there is concern among the Senate GOP leadership that they don't yet have the votes locked down to pass the bill. Republicans can only lose three votes when this bill comes up for a final vote.

There's been a very aggressive effort by GOP leadership to work on Sen. Lisa Murkowski, who has so far not said how she intends to vote on this package.

In the last hour, Murkowski has been seen on the floor deep in conversation at various points with Majority Leader John Thune, Republican whip John Barrasso, Finance Committee Chairman Mike Crapo and fellow Alaskan Sen. Dan Sullivan.

Murkowski has been a hold out, expressing concern over Medicaid and SNAP provisions.

Thune, walking off the floor, said he and Murkowski were "just chatting". But he's not yet denoted a clear path out of this whip count predicament.

Thune was asked, as he walked off the floor, if he could pull the bill back or if he'd be forced to hold a final passage vote on the bill, even if he knows it will fail.

"Those are options I don't want to have to worry about," Thune said.

At present, the whip count is a real problem for Thune. Sens. Thom Tillis and Rand Paul are expected to cast votes against the bill. Losing Murkowski or Sen. Susan Collins could be a real problem.

There's also not yet a clear path forward on how an amendment that aims to further reduce Medicaid spending will be dealt with. The outcome of that amendment vote could sway voters like Sens. Mike Lee and Rick Scott.

At the beginning of this vote, Senators overwhelmingly voted in favor of stripping out provisions in the bill that would limit states from passing rules to regulate artificial intelligence.

The move came after Sen. Marsha Blackburn and Sen. Ted Cruz struck a deal on how to keep the moratorium in the bill, before Blackburn reneged early Tuesday morning.

Before this tranche of votes that Thune teed up, Sen. Joni Ernst's amendment that bars millionaires from collecting unemployment income support passed by voice vote.

-ABC News' Allison Pecorin

The Senate vote-a-rama has been going on for nearly 19 hours. Senators are now seated at their desks on the floor, some with weary faces, others wearing blankets and fuzzy socks -- and many drinking coffee.

There is still no clear indication as to when the session will come to a close or when the Senate will proceed to a final vote.

The Senate just completed voting on an amendment by Sen. Mike Lee that aimed to strip out wind and solar tax credits from this bill. It failed by a vote of 22-78. Lee's amendment was closely watched partially because members of the House Freedom Caucus wanted it to pass.

Lee's amendment was the 33rd vote that the Senate has taken in this vote-a-rama. There are, at present, three more votes queued up. Aides told ABC News those next votes will not be the last of the session, but it is not unclear how many more may follow.

Majority Leader Sen. John Thune has now asked his colleagues to keep the next round of votes to 10 minutes each. The longer this goes, the faster we expect senators to vote.

-ABC News' Allison Pecorin

President Donald Trump responded to Elon Musk's criticisms of the "One Big Beautiful Bill" on Truth Social early Tuesday, suggesting he could direct DOGE to probe subsidies awarded to the billionaire's companies.

In recent days, Musk has criticized Trump's megabill as an "utterly insane" piece of legislation that will "destroy millions of jobs in America and cause immense strategic harm to our country!" Musk has also threatened to support primary campaigns against lawmakers who back the bill.

In response, Trump said early Tuesday that Musk "may get more subsidy than any human being in history, by far, and without subsidies, Elon would probably have to close up shop and head back home to South Africa."

"No more Rocket launches, Satellites, or Electric Car Production, and our Country would save a FORTUNE," Trump wrote. "Perhaps we should have DOGE take a good, hard, look at this? BIG MONEY TO BE SAVED!!!"

The president also said Musk "knew, long before he so strongly Endorsed me for President, that I was strongly against the EV Mandate. It is ridiculous, and was always a major part of my campaign. Electric cars are fine, but not everyone should be forced to own one."

-ABC News' Alex Ederson

Sen. Susan Collins blamed Democrats for tanking her amendment to boost the GOP megabill's rural hospital relief fund.

She called Democratic senators "hypocrites" for claiming to care about protecting Medicaid and then voting against her efforts to lessen the impacts of the "One Big Beautiful Bill" on hospitals in rural areas.

"I was surprised at the hypocrisy of the Democrats on it, had they voted for it would have passed easily," Collins told reporters after the vote early Tuesday morning.

Georgia Sens. Jon Ossoff and Raphael Warnock were the only two Democrats out of 22 senators who supported Collins' amendment.

"They complained repeatedly about the distribution in this bill of Medicaid cuts, hurting individuals in rural hospitals and tax cuts being extended for people who are wealthy. And yet, when we tried to fix both those problems, They took a very hypocritical approach," Collins said.

Collins said the outcome of this amendment would have "absolutely no impact" on her decision to support the bill's final passage, however.

It's still unclear how Collins will vote. "We'll see what the final bill looks like," she said.

-ABC News' Isabella Murray