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The Senate floor is currently in a state of paralysis while Republican leaders push for the support necessary to bring President Donald Trump's "Big Beautiful Bill" to a final vote on the Senate floor.

Majority Leader John Thune does not yet appear to have locked down the necessary 51 votes he needs to bring the bill up during final passage.

One of the main targets of the GOP leadership's efforts is Sen. Lisa Murkowski, whose indecision comes after reports that the Senate parliamentarian may have ruled some carve out provisions meant for her home state of Alaska's Medicaid recipients out of order.

Also under pressure are Sens. Mike Lee and Rick Scott -- who have yet to receive a vote on their amendment that strips back additional funding for Medicaid -- plus Sen. Susan Collins, whose proposed amendment to boost the rural hospital relief fund was voted down by her colleagues early Tuesday morning.

Sen. Thom Tillis is expected to vote against the bill because of Medicaid concerns.

Sen. Rand Paul had also been expected to vote against the megabill. But the Kentucky senator reportedly has an amendment up for consideration that would significantly reduce the amount of money attributed to raise to the federal debt limit.

The current bill raises the debt limit by $5 trillion dollars. Paul's amendment would raise it by only $500 billion.

This last-ditch move might prove enough to win over Paul's vote, which could end up proving critical if Thune loses some of his other members. But it puts Republicans in a bind potentially within the year.

The reason Republicans are including a debt limit hike is because it allows them to raise the debt limit without any Democratic support.

Raising the debt limit by only $500 billion means Republicans may have to try to raise it again in a relatively short amount of time, and that would mean negotiating with Democrats who would likely seek concessions in exchange for their votes.

Tillis said that would be a decision that Trump would have to be involved in making.

-ABC News' Allison Pecorin

As more amendments are called for votes, Republicans continue to huddle behind the scenes to chart a path to ending the marathon vote-a-rama and passing President Donald Trump's megabill.

It appears increasingly clear there is concern among the Senate GOP leadership that they don't yet have the votes locked down to pass the bill. Republicans can only lose three votes when this bill comes up for a final vote.

There's been a very aggressive effort by GOP leadership to work on Sen. Lisa Murkowski, who has so far not said how she intends to vote on this package.

In the last hour, Murkowski has been seen on the floor deep in conversation at various points with Majority Leader John Thune, Republican whip John Barrasso, Finance Committee Chairman Mike Crapo and fellow Alaskan Sen. Dan Sullivan.

Murkowski has been a hold out, expressing concern over Medicaid and SNAP provisions.

Thune, walking off the floor, said he and Murkowski were "just chatting". But he's not yet denoted a clear path out of this whip count predicament.

Thune was asked, as he walked off the floor, if he could pull the bill back or if he'd be forced to hold a final passage vote on the bill, even if he knows it will fail.

"Those are options I don't want to have to worry about," Thune said.

At present, the whip count is a real problem for Thune. Sens. Thom Tillis and Rand Paul are expected to cast votes against the bill. Losing Murkowski or Sen. Susan Collins could be a real problem.

There's also not yet a clear path forward on how an amendment that aims to further reduce Medicaid spending will be dealt with. The outcome of that amendment vote could sway voters like Sens. Mike Lee and Rick Scott.

At the beginning of this vote, Senators overwhelmingly voted in favor of stripping out provisions in the bill that would limit states from passing rules to regulate artificial intelligence.

The move came after Sen. Marsha Blackburn and Sen. Ted Cruz struck a deal on how to keep the moratorium in the bill, before Blackburn reneged early Tuesday morning.

Before this tranche of votes that Thune teed up, Sen. Joni Ernst's amendment that bars millionaires from collecting unemployment income support passed by voice vote.

-ABC News' Allison Pecorin

The Senate vote-a-rama has been going on for nearly 19 hours. Senators are now seated at their desks on the floor, some with weary faces, others wearing blankets and fuzzy socks -- and many drinking coffee.

There is still no clear indication as to when the session will come to a close or when the Senate will proceed to a final vote.

The Senate just completed voting on an amendment by Sen. Mike Lee that aimed to strip out wind and solar tax credits from this bill. It failed by a vote of 22-78. Lee's amendment was closely watched partially because members of the House Freedom Caucus wanted it to pass.

Lee's amendment was the 33rd vote that the Senate has taken in this vote-a-rama. There are, at present, three more votes queued up. Aides told ABC News those next votes will not be the last of the session, but it is not unclear how many more may follow.

Majority Leader Sen. John Thune has now asked his colleagues to keep the next round of votes to 10 minutes each. The longer this goes, the faster we expect senators to vote.

-ABC News' Allison Pecorin

President Donald Trump responded to Elon Musk's criticisms of the "One Big Beautiful Bill" on Truth Social early Tuesday, suggesting he could direct DOGE to probe subsidies awarded to the billionaire's companies.

In recent days, Musk has criticized Trump's megabill as an "utterly insane" piece of legislation that will "destroy millions of jobs in America and cause immense strategic harm to our country!" Musk has also threatened to support primary campaigns against lawmakers who back the bill.

In response, Trump said early Tuesday that Musk "may get more subsidy than any human being in history, by far, and without subsidies, Elon would probably have to close up shop and head back home to South Africa."

"No more Rocket launches, Satellites, or Electric Car Production, and our Country would save a FORTUNE," Trump wrote. "Perhaps we should have DOGE take a good, hard, look at this? BIG MONEY TO BE SAVED!!!"

The president also said Musk "knew, long before he so strongly Endorsed me for President, that I was strongly against the EV Mandate. It is ridiculous, and was always a major part of my campaign. Electric cars are fine, but not everyone should be forced to own one."

-ABC News' Alex Ederson