At a briefing at the Pentagon on Wednesday, Defense Secretary Pete Hegseth confirmed that a U.S. submarine used a torpedo to sink an Iranian warship named after Islamic Revolutionary Guard Corps commander Qasem Soleimani, who was killed in a 2020 drone strike ordered by President Trump.

Joint Chiefs Chairman Gen. Dan Caine said this was the first time since 1945 that a U.S. Navy submarine “sunk an enemy combatant ship using a single Mark 48 torpedo to achieve immediate effect, sending the warship to the bottom of the sea.”

The Iranian warship, which was near Sri Lanka, had 180 people on board, Sri Lankan authorities said, according to the Associated Press. Thirty-two people were rescued and 87 bodies have been recovered, according to the AP. The ship had just completed participating in a large, multinational Indian naval exercise.

Caine acknowledged that there are a lot of questions about the U.S. missile stockpile, but he expressed confidence that the U.S. has enough munitions to continue military operations against Iran. However, he cautioned that he cannot provide details due to operational security reasons.

-ABC News' Luis Martinez

Iran's top national security official on Wednesday warned the U.S. and Israel that the killing of Iranian Supreme Leader Ali Khamenei "will exact a heavy price from you."

"Mr. Trump, with Netanyahu's clownish antics, dragged the American people into an unfair war with Iran," Ali Larijani, secretary of Iran's Supreme National Security Council, wrote in a post on X. "Now let him do the math: with over 500 American troops killed (in these past few days), is it still 'America First,' or 'Israel First'? The saga continues."

"The martyrdom of Imam Khamenei will exact a heavy price from you. God willing,” he added.

CENTCOM has confirmed that six Americans have been killed in the attacks.

-ABC News’ Somayeh Malekian

At least 940 people have been reported killed in Iran, with 174 cities across the country affected by the conflict so far, a spokesperson for the Iranian Red Crescent Society told Iran's semiofficial SNN news agency.

"The evidence in front of us since the 12-day war was that Iran had no intention of actually negotiating a nuclear deal that truly meant they did not have a pathway to the nuclear bomb," Defense Secretary Hegseth said at the Pentagon briefing.

Hegseth said that negotiators Jared Kushner and Steve Witkoff "poured into that negotiation, giving them every single possible opportunity to release that that ambition, and they didn't. And the intelligence that we saw [showed] they didn't intend to do it in good faith – that they had the intentions eventually to get to a place where they could have that a conventional shield to block their nuclear capabilities.”

-ABC News Steve Beynon