As Iran retaliates, largest US military base in Middle East hit by ballistic missile, Qatar says

No one was injured, according to the Qatari Ministry of Defense.

President Donald Trump announced "major combat operations" against Iran on Saturday, with daytime strikes in the joint U.S.-Israel attack targeting military and government sites, officials said.

On Sunday, Iranian state television confirmed that Ayatollah Ali Khamenei was among those killed by airstrikes in Tehran on Saturday.

Iran is responding to the U.S.-Israeli operation with missile and drone attacks targeting Israel, regional U.S. bases and Gulf nations. American diplomatic facilities have also been attacked.

In Lebanon, Israel is intensifying its long-running strike campaign against the Iranian-aligned Hezbollah militia.

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US Embassy in Oman issues shelter-in-place order

The U.S. Embassy in Muscat, Oman, on Sunday issued a shelter-in-place order for all Americans in the country due to "ongoing activity outside of Muscat."

The northern coast of Oman, on which Muscat is located, faces the southeastern coast of Iran across the Gulf of Oman. The country has traditionally played a mediating role between Iran and the U.S.

As of Sunday morning, Oman was the only Gulf nation not to have been attacked by Iran.


Khamenei killed in 'opening blow,' Israeli defense minister says

Ayatollah Ali Khamenei was killed during the "opening blow" of the U.S.-Israel operation on Saturday, Israeli Defense Minister Israel Katz said in a post on X on Sunday.

Katz congratulated Israeli Prime Minister Benjamin Netanyahu for his "leadership and determination," and the Israel Defense Forces for its "brilliant execution."

-ABC News' Jordana Miller and Ellie Kaufman


State media confirms deaths of 2 senior Iranian officials

Iranian state media confirmed the deaths of Rear Adm. Ali Shamkhani, the secretary of the Defense Council, and Maj. Gen. Mohammad Pakpour, the commander-in-chief of the Islamic Revolutionary Guards Corps, in strikes on Saturday.

ABC News' Somayeh Malekian and Ellie Kaufman


Iran's parliament speaker warns protesters not to side with enemies

Iran's parliament speaker, Mohammad Bagher Qalibaf, said in a speech on Sunday morning that the U.S. and Israel had crossed a red line in launching their attacks on Iran, vowing strong retaliation.

In his speech, which was broadcast on Iranian state television, Qaribah also addressed Iranian protesters directly, acknowledging their legitimate concerns but adding that no one should side with Iran's enemies.

Qalibaf said that the heart of the Iranian nation was broken after the death of Ayatollah Ali Khamenei and pledged that the path he forged would continue.

ABC News' Somayeh Malekian and Ellie Kaufman