As Iran retaliates, largest US military base in Middle East hit by ballistic missile, Qatar says

No one was injured, according to the Qatari Ministry of Defense.

President Donald Trump announced "major combat operations" against Iran on Saturday, with daytime strikes in the joint U.S.-Israel attack targeting military and government sites, officials said.

On Sunday, Iranian state television confirmed that Ayatollah Ali Khamenei was among those killed by airstrikes in Tehran on Saturday.

Iran is responding to the U.S.-Israeli operation with missile and drone attacks targeting Israel, regional U.S. bases and Gulf nations. American diplomatic facilities have also been attacked.

In Lebanon, Israel is intensifying its long-running strike campaign against the Iranian-aligned Hezbollah militia.

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UAE says it has intercepted more than 100 Iranian missiles

The UAE intercepted 137 ballistic missiles and 195 drones launched from Iran towards the country since the start of the Iranian attack, the UAE's Ministry of Defense said in a post on X.

Out of the 137 missiles launched towards the UAE, 132 were destroyed, and five fell into the sea, the ministry said.

Out of the 209 drones detected, 195 were intercepted. The other 14 landed within UAE territory and waters, "causing some" damage, the ministry said.

-ABC News' Victoria Beaule


1 dead, more than 25 injured in Israel after attack

More than 25 people have been injured and at least one person has died in Israel on Saturday, according to Icholov Hospital, Tel Aviv Medical Center and Magen David Adom, Israel’s national emergency medical, disaster, ambulance and blood bank service.

Out of the 25 injured who have been evacuated and taken to the Ichilov Emergency Department, four are in moderate condition. The others are in mild condition.

Seven of the injured are children, but have minor injuries.

-ABC News' Dana Savir and Ellie Kaufman


Homeland Security issues alert to local law enforcement, including cyber attack threat

The Department of Homeland Security has issued a critical incident alert following the U.S. strikes on Iran.

"Although a large-scale physical attack is unlikely, Iran and its proxies probably pose a persistent threat of targeted attacks in the Homeland, and will almost certainly escalate retaliatory actions--or calls to action--if reports of the Ayatollah's death are confirmed," according to the bulletin, which was obtained by ABC.

"In the short-term, we are most concerned that Iran-aligned hacktivists will conduct low-level cyber attacks against US networks, such as website defacements and distributed denial-of-service attacks," the alert added.

-ABC News' Luke Barr and Mike Levine


Rubio cancels planned Israel trip, State Dept. says

Rubio will not travel to Israel on Monday as previously scheduled, according to a post by Dylan Johnson, the State Department’s assistant secretary for global public affairs.

-ABC News' Shannon Kingston