Two people in Israel are dead following an Iranian missile barrage, according to Magen David Adom, the Israeli emergency response organization.

A man and woman died from "serious shrapnel injuries" in Ramat Gan, near Tel Aviv, the organization said.

Search and rescue crews responded to several sites in central Israel following reports of impacts from Iranian launches, the Israel Defense Forces said.

Iran's Supreme National Security Council has confirmed that senior official Ali Larijani is dead.

In a statement published by the semi-official Tasnim news agency on Tuesday, the council said Larijani died alongside his son, a security deputy of the secretariat, and several members of his protection team. It did not provide details on how or where the deaths occurred.

Earlier Tuesday, the Israeli minister of defense said Larijani, the head of Iran's Supreme National Security Council, was killed in an overnight attack on Iran.

Hours after National Counterterrorism Center Director Joe Kent resigned over his objections to the war in Iran. Director of National Intelligence Tulsi Gabbard on Tuesday publicly backed President Donald Trump’s authority to determine what constitutes an imminent threat on the war.

“As our Commander in Chief, he is responsible for determining what is and is not an imminent threat, and whether or not to take action he deems necessary to protect the safety and security of our troops, the American people and our country,” Gabbard tweeted.

In the lengthy X post on Tuesday, Gabbard stopped short of directly addressing Kent’s resignation, or Kent by name.

“The Office of the Director of National Intelligence is responsible for helping coordinate and integrate all intelligence to provide the President and Commander in Chief with the best information available to inform his decisions,” Gabbard added.

“After carefully reviewing all the information before him, President Trump concluded that the terrorist Islamist regime in Iran posed an imminent threat and he took action based on that conclusion,” she continued.

More than a dozen unmanned MQ-9 Reaper drones have been lost in combat as part of the operations against Iran, two U.S. officials confirmed to ABC News.

The Reaper drones were either lost to Iranian missile fire or were destroyed on the ground by incoming fire.

Reaper drones can be used as reconnaissance aircraft, but they are also equipped with Hellfire missiles used to strike at targets.

The loss of this number of Reapers is indicative of how many of these key unmanned aircraft must be operating as part of the U.S. operations against Iran.

The loss of the drones in the Iran war was first reported by the Wall Street Journal.