President Joe Biden and Judge Ketanji Brown Jackson are currently in the Roosevelt Room of the White House watching this historic vote, according to the White House print pooler.

Vice President Kamala Harris, as president of the Senate, presided over the Senate chamber to announce the roll call vote.

Both party leaders spoke ahead of Judge Jackson's confirmation vote, with Vice President Kamala Harris, as president of the Senate, presiding over the chamber for the historic occasion.

Republican leader Mitch McConnell said he "applaud[ed]" Republicans for handling Jackson's confirmation with the seriousness it deserves," a characterization rejected b Democrats.

Majority Leader Chuck Schumer, meanwhile, celebrated the historic nature of the nomination.

"In our nation's history, 115 individuals have been confirmed by this body to serve on the Supreme Court of the United States. Of those, 108 have been white men, only 4 have been women, only 2 have been African American," Schumer said. "But Ketanji Brown Jackson will be the first African American woman ever to hold the title of Justice. Think about the impact that will have on our democracy."

"This is one of the great moments of American history," Schumer said. "This is a great moment for Judge Jackson but it is an even greater moment for America as we rise to a more perfect union."

Vice President Kamala Harris, presiding over the Senate chamber, called for a roll call vote for Judge Jackson’s Senate confirmation.

Jackson is expected to watch the roll call vote with her family in Washington.

As the confirmation vote nears, Senate Judiciary Chair Dick Durbin, D-Ill., who presided over Jackson's confirmation hearings, called her ascension to the high court "a glass shattering achievement for America."

"Today, the members of this Senate have the opportunity to take a monumental step forward. We will vote to confirm a once in a generation legal talent, a jurist with outstanding credentials and a lifetime of experience and the first-ever African American woman to serve as Justice of the Supreme Court," Durbin said.

Durbin briefly walked the Senate through some of the struggles African Americans and women have faced in this country, asking senators to consider that when the Supreme Court first met in the Capitol building in February of 1801, there were one million slaves in a nation of five million people.

"Women had no place in that first Supreme Court chamber, and Black women would only enter to clean it in the dark of night," he said. "We know what followed. Americans battled in slavery, saw a bloody civil war, decades of efforts to break down racial barriers -- and the efforts continue to this day."

But with Jackson's nomination, Durbin said millions of Americans will see themselves represented in her.

"This confirmation of the first Black woman to the Supreme Court honors the history that has come before it It honors the struggles of the past of the men and women who waged them. And this confirmation draws America one step closer one step to healing our nation," he said.

After drawing a contrast between America of the past and present, from a nation that once had hundreds of thousands of enslaved people to that of a "more perfect union," Senate Judiciary Chairman Dick Durbin, D-Ill., defended Jackson against concerns voiced by Minority Leader Mitch McConnell and some other Republicans that, as a former public defender, she will have "special empathy" as some Democrats touted.

"The cameras and the lights here today can make it easy to forget that at its core the responsibility you seek is one of service -- and I'm fully confident you'll serve Americans from all walks of life, all backgrounds fairly and faithfully," Durbin said. "Now there may be some who claim without a shred of evidence that you'll be a rubber stamp for this president. For those would-be critics, I have four words: Look at the record," he added.

Pointing out that the committee has already scoured her records now on four different occasions and seen "every published and reported word you've written or spoken," Durbin said, "For those who say they need more, I would answer that you've sat down personally with every member of the dais of the committee, Democrats and Republicans."

In what's likely to become a theme for Democrats, Sen. Patrick Leahy, D-Vt., echoed Durbin's defense.

"Judge Jackson is not anti-law enforcement. She hails from a law enforcement family. She's also won the support of preeminent national law enforcement organizations including the national fraternal order of police," Leahy said. "And no, she's not soft on crime. Her background as a federal public defender would bring an informed perspective of our criminal justice system to the Supreme Court."