17 U.S. service members have been killed since the war in Iran began.
President Donald Trump announced "major combat operations" against Iran on Feb. 28, with massive joint U.S.-Israeli strikes targeting military, government and infrastructure sites.
Delegations from the U.S. and Iran entered negotiations in June aimed at a war-ending deal based on a memorandum of understanding signed by both countries.
The U.S. and Iran have nonetheless continued to exchange relatively limited strikes despite the signing of the memorandum and amid the continuation of peace talks, with the strategic Strait of Hormuz the primary flashpoint.
In a post on X, U.S. Central Command said it began launching "a wave of strikes" against Iran at around 6 a.m. ET on Wednesday.
"The strikes are designed to further degrade military capabilities Iranian forces have used to attack commercial shipping in the Strait of Hormuz," the post said.
-ABC News' Lauren Minore
The Islamic Revolutionary Guard Corps claimed to have targeted U.S. military bases and assets in Bahrain, Kuwait and Jordan in strikes launched in the early hours of Wednesday.
Bahrain reported that its alarm sirens were activated, while Kuwait said its air defenses intercepted six missiles and 33 drones. Jordan said its air defenses intercepted and shot down three Iranian missiles.
-ABC News’ Morgan Winsor and Guy Davies
The Jordan News Agency reported that the country's military intercepted three ballistic missiles that entered national airspace from Iranian territory in the early hours of Wednesday morning.
The military reported no damage or casualties, the agency said, citing a source in the armed forces' General Command.
U.S. forces completed another round of strikes against Iran, U.S. Central Command said in a statement late Tuesday night.
The statement says the U.S. hit "dozens of military targets near the Strait of Hormuz and Iranian coastal areas" during what it described as a "seven-hour wave" of attacks "to further degrade Iran's ability to threaten commercial shipping and civilian crews."
The strikes took place the same day the U.S. reimposed a naval blockade against vessel traveling to or from Iranian ports, CENTCOM said.
