Iran live updates: US launches 2nd round of strikes on Iran on Wednesday

President Donald Trump said the U.S. might have to wipe out Iran's Islamic Revolutionary Guard Corps, saying it cannot be negotiated with. He claimed Iran called the U.S. on Wednesday asking to meet.

When asked whether he believes that he might have to take out the IRGC because he's concluded he cannot negotiate with them, Trump told Fox Business, "yeah," but added he has to "see what's happening."

The U.S. has launched another wave of airstrikes again, the second wave on Wednesday, U.S. Central Command said.

"At 3 p.m. ET, U.S. forces launched operations for a second wave of strikes today against Iran. The strikes are targeting Iranian military capabilities used to threaten vessels freely transiting through the Strait of Hormuz, an international waterway vital to global commerce. The U.S. military is holding Iran accountable at the Commander in Chief's direction," CENTCOM said in a statement.

Vice President JD Vance expressed uncertainty over next steps with Iran, saying he expects it to be "really messy," in an interview released Wednesday.

He also claimed that the U.S. would not be involved in an indefinite bombing campaign and declined to divulge his personal stance on the war.

“I don't know exactly where this is going to go, but I think fundamentally we are on the right trajectory. It's just going to be really messy, and there's going to be a lot of stops and starts,” Vance said.

The vice president claimed the mid-ceasefire escalation from Iran was the result of a “freak out” among hard-liners within Iran over the increase in oil passing through the Strait after the MOU was signed, and that “pragmatists” in Iran are still looking to negotiate.

Vance said the U.S. is currently navigating a “delicate diplomatic dance,” adding that they are still “trying to talk to the pragmatists.”

After giving Iran until next week to come back to the negotiating table or face bombing of its critical infrastructure, President Donald Trump said on Wednesday that he didn't like giving deadlines.

"I don't like giving deadlines, but they pretty much know. They know the story. They better behave," Trump told reporters.

Trump had been asked if he planned to give Iran a specific deadline before he started bombing bridges.